Advise sufferers of the chance of life-threatening respiratory despair, which includes facts that the risk is biggest when starting off acetaminophen and codeine phosphate tablets or in the event the dosage is increased, Which it can take place even at recommended dosages.
Opioid antagonists, for instance naloxone, are precise antidotes to respiratory despair resulting from opioid overdose. For clinically important respiratory or circulatory despair secondary to acetaminophen and codeine overdose, administer an opioid antagonist.
Concomitant use needs to be reserved to be used in people for whom option treatment method solutions are inadequate. If essential, limit dose and length to your minimum amount required and stick to individuals for indicators and indicators of respiratory melancholy and sedation.
Acetaminophen and codeine phosphate tablets need to be prescribed only by Health care specialists who're knowledgeable about the use of opioids and how to mitigate the associated challenges.
Retain a summary of each of the solutions you utilize (which include prescription/nonprescription medication and herbal products and solutions) and share it with all your doctor and pharmacist. Tend not to get started, end, or alter the dosage of any medicines without having your doctor's acceptance.
Opioids cross the placenta and could make respiratory despair and psycho-physiologic consequences in neonates. An opioid antagonist, for instance naloxone, have to be available for reversal of opioid-induced respiratory depression during the neonate. Acetaminophen and codeine phosphate tablets aren't recommended for use in pregnant women throughout or quickly before labor, when other analgesic strategies are more appropriate.
Retailer at area temperature clear of dampness and heat. Keep track of your medicine. Codeine is usually a drug of abuse and click here you ought to be informed if anybody is using your medicine improperly or with out a prescription.
Focus-Efficacy Relationships The minimum amount successful analgesic focus will vary widely among get more info sufferers, especially among the people who have been Formerly addressed with extended-launch agonist opioids.
Accidental Ingestion Accidental ingestion of even 1 dose of acetaminophen and codeine phosphate tablets, Specifically by little ones, may result in a fatal overdose website of acetaminophen and codeine (see WARNINGS).
Abuse of and habit to click here opioids in some men and women will not be accompanied by concurrent tolerance and signs of Actual physical dependence. Moreover, abuse of opioids can come about in the absence of addiction.
Sufferers ought to be instructed to not discontinue this drug without the need of initial talking about a tapering strategy with their healthcare supplier.
Fetal/Neonatal Adverse Reactions Utilization of opioid analgesics for an prolonged time period through pregnancy for medical or nonmedical purposes can result in physical dependence within the neonate and neonatal opioid withdrawal syndrome Soon after birth.
If concomitant use using a CYP2D6 inhibitor is important, evaluate the affected person for indications of reduced efficacy or opioid withdrawal and take into account increasing the acetaminophen and codeine phosphate website tablets dosage.
Begin to see the conclude of this leaflet for an entire listing of substances in Viagra®. What must I inform my healthcare supplier right before having Viagra® or generic Viagra®?